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KMID : 0356919940270010054
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Korean Journal of Anesthesiology
1994 Volume.27 No. 1 p.54 ~ p.59
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The Effect of Transdermal Scopolamine Patch on Nausea and Vomiting after Epidural Injection of Morphine
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Abstract
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Sixty patients, undergoing major gynecologic surgery with lumbar epidural anesthesia, were randomly selected 32 patients to apply a transdermal scopolamine patch (Kimite(r) MyoungMoon, Korea) on the skin behind one ear. We were divided into 2
groups.
Control group; epidural morphine 4mg were given and not applied scopolamine patch. Experimental group; epidural morphine 4mg were given and applied transdermal scopolamine patch on the skin behind her ear at the night before surgery.
They were followed up for 3 days postoperatively and statistical analysis was done. There was a significant (P<0.05) reduction in nausea and vomiting between experimental group and control group. There was no significant incresed incidence in
scopolamine side effects. However, despite receiving transdermal scopolamine patch there was still a high incidence (43.8%) of nausea and vomiting.
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